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Clinical Quality Lead

  • argenx
Ghent, Belgium
Full-time
Published:
  • argenx
Ghent, Belgium
Full-time
Published:

PURPOSE OF THE FUNCTION:

  • Act as the quality lead for all Externally Sponsor Research, Non-interventional studies, Early Access Programs, Name Patient Programs and other non traditional clinical studies;

  • Drive towards real time quality oversight and consistent high-quality standards of the global clinical trials, both pre and post marketing;

  • Support the Clinical Quality Vendor Lead to ensure harmonized quality vendor oversight.


REPORTING LINE:

  • Head of Clinical Quality.


ROLES AND RESPONSIBILITIES:

  • Serve as primary Quality point of contact for Externally Sponsor Research, Non-interventional studies, Early Access Programs, Name Patient Programs and other non traditional clinical studies;

  • Be the Quality point of contact for Global Medical Affairs;

  • Lead the GCP quality oversight for assigned trials, collaborating closely with trial teams to uphold high-quality standards;

  • Oversee the clinical trial audit programs, including leading the audit site selection process for study-specific audit plans in collaboration with CTT(s), and ensuring timely audit conduct, reporting, review, and closeout in accordance with argenx processes;

  • Work with Trial Team to produce GCP quality system metrics for real-time quality monitoring and reporting (e.g., audits, deviations, CAPAs), and conduct trend analysis for management reporting;

  • Drive the investigation of trial quality events and define necessary corrective and preventive measures;

  • Lead clinical trial inspection readiness activities to ensure preparedness;

  • Provide QA input during the creation/revision of argenx clinical procedural documents for GCP compliance;

  • Oversee the relationship and performance of clinical partners/vendors to maintain quality standards (incl. vendor qualification).


SKILLS AND COMPETENCIES:

  • Experience in Quality Oversight for Externally Sponsor Research, Non-interventional studies, Early Access Programs, Name Patient Programs and other non traditional clinical studies;

  • In‐depth knowledge of all Clinical Trial related FDA and EU regulations and ICH Guidelines;

  • Ability to create a comprehensive study quality oversight plan and audit program and lead the execution thereof;

  • Stakeholder management skills.


EDUCATION, EXPERIENCE AND QUALIFICATIONS:

  • Minimum 7 years clinical trial experience;

  • Minimum 5 years quality assurance experience;

  • FDA, EMA, MHRA, PDMA Inspection experience;

  • Capable of building effective relationships with internal and external stakeholders;

  • Able to operate in a dynamic surrounding of a fast growing biotech company with challenging timeline;

  • Life science educational background;

  • Fluent in English.

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